ALS Center of Excellence

Pranger ALS Clinic

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Latest News

ALS Risk Higher Among Production Workers

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“Research Into Preventing ALS…”

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portrait of Dr. Eva Feldman in her lab

Dr. Feldman Given Highest University of Michigan Honor

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Multidisciplinary Team Publishes Paper on ALS Occupational Risk

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The ANA Q&A: Dr. Eva Feldman on ALS

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Stem Cell Trial

Stem cell transplantation study for the treatment of ALS – Phase 2

The phase 2 trial focused on the safety and maximum tolerated dose of Human Spinal Cord Derived Neural Stem Cell Transplantation. This study expanded on the work of the phase 1 study directed by Eva L. Feldman, M.D., Ph.D., who is the principal investigator and director of the first-ever FDA-approved human clinical trial of stem cells injected directly into the spinal cords of ALS patients.

Phase 1 of the trial, designed to study the safety of the procedure, was completed in 2013 with no significant adverse side effects to patients. Phase 2 included 15 additional participants, the last 3 of which received 8 million stem cells injected into the lumbar spinal cord followed by 8 million stem cells injected into the cervical spinal cord. Data from these studies suggest that the procedure is safe for persons with ALS (https://www.ncbi.nlm.nih.gov/pubmed/29928656). We do not currently have an enrolling stem cell trial.

https://clinicaltrials.gov/show/NCT01730716

Future trials

Information regarding future trials is anticipated to be announced by Neuralstem (https://www.neuralstem.com/).

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ALS Center of Excellence at Michigan Medicine ALS Infographic

ALS Brochure

ALS Brochure

 

 

 

 

 

Resources

Organizations

  • ALS Association
  • ALSA-Michigan Chapter
  • Ann Arbor Active Against ALS
  • ALSA-Northern Ohio Chapter
  • ALS of Michigan
  • National ALS Registry
  • Northeast ALS Consortium
  • Muscular Dystrophy Association

Services

  • Veterans Benefits
  • Social Security Benefits

Useful Links

  • U-M Stem Cell Research
  • Center for Stem Cell Biology
  • Human Embryonic Stem Cell Research
  • Society for Stem Cell Research

RSS Research News

  • U-M to establish new Institute for Firearm Injury Prevention
  • U-M Depression Center to be named for Eisenberg family, in recognition of $30M in giving
  • Research on aging expands at U-M with $15M in new grants

Contact Information

Michigan Medicine
1500 E. Medical Center Drive
Ann Arbor, MI 48109
Phone: 734-936-4000
Contact Michigan Medicine

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  • About UMHS
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  • Home
  • About
    ▼
    • What Is ALS?
    • Scott L. Pranger
    • National Advisory Board
    • Faculty & Staff
    • ALS Center of Excellence Brochure
  • Clinic
    ▼
    • Services
    • Your Visit to the ALS Clinic
    • Patient Portal
    • Durable Medical Equipment
    • Frequently Asked Questions
  • Research
    ▼
    • Clinical Trials
    • Observational Studies
    • Participate in Research at U-M
  • News
  • Patient Care Guide
    ▼
    • Living with ALS
    • Nutrition
    • Patient & Family Support
  • Contact
  • NeuroNetwork
  • Make A Gift