ALS Center of Excellence

Pranger ALS Clinic

  • Home
  • About
    • What Is ALS?
    • Scott L. Pranger
    • National Advisory Board
    • Faculty & Staff
    • ALS Center of Excellence Brochure
  • Clinic
    • Services
    • Your Visit to the ALS Clinic
    • Patient Portal
    • Durable Medical Equipment
    • Frequently Asked Questions
  • Research
    • Clinical Trials
    • Observational Studies
    • Stem Cell Trial
    • Our Publications
    • Participate in Research at U-M
  • News
  • Patient Care Guide
    • Nutrition
    • Living with ALS
    • Mobility & Independence
    • Patient & Family Support
  • Contact
  • NeuroNetwork
  • Make A Gift

Clinical Trials

Ongoing Trials

Healey Center Platform Trial for ALS
The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. In this trial, multiple drugs (Regimen A – Zilucoplan; Regimen B – Verdiperstat; Regimen C – CNM-Au8) for ALS will be tested simultaneously or sequentially. Each drug will be tested in a regimen. Each regimen consists of a placebo-controlled trial, meaning that the active drug and matching placebo will be tested in each regimen.
Related News: U-M ALS Center of Excellence Participates in National Clinical Drug Trial

Safety Study of Oral Edaravone Administered in Subjects With ALS
The objective of this study is to evaluate the long-term safety and tolerability of oral edaravone in subjects with Amyotrophic Lateral Sclerosis (ALS) over 24 and 48 weeks.

An up-to-date listing of our studies can be found here

Completed Trials

Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS (REFALS)

AMX0035 in Patients With Amyotrophic Lateral Sclerosis (CENTAUR)

A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) (FORTITUDE-ALS)

Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (Mexiletine-2)

Clinical Trial of Ezogabine (Retigabine) in ALS Subjects

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (VITALITY-ALS)

Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)

For questions on clinical trials at the University of Michigan, please email Jayna Duell at jkballar@med.umich.edu

ALS Brochure

ALS Brochure


COVID-19 Update

COVID-19 Resources

Join the National ALS Registry. With your help, we can advance research. Learn More.

Resources

Organizations

  • ALS Association
  • ALSA-Michigan Chapter
  • Ann Arbor Active Against ALS
  • ALSA-Northern Ohio Chapter
  • ALS of Michigan
  • National ALS Registry
  • Northeast ALS Consortium
  • Muscular Dystrophy Association

Services

  • Veterans Benefits
  • Social Security Benefits

Newsletter Signup

Subscribe to our mailing list for updates regarding our clinic and research

Useful Links

  • U-M Stem Cell Research
  • Center for Stem Cell Biology
  • Human Embryonic Stem Cell Research
  • Society for Stem Cell Research

RSS Research News

  • Research on aging expands at U-M with $15M in new grants
  • U-M to Conduct Clinical Trial to Test AstraZeneca COVID-19 Vaccine
  • Michigan Medicine and three other medical centers receive $7 million for COVID-19 outpatient convalescent plasma therapy trial

Contact Information

Michigan Medicine
1500 E. Medical Center Drive
Ann Arbor, MI 48109
Phone: 734-936-4000
Contact Michigan Medicine

Connect With Us

Copyright © 2021 Regents of the University of Michigan · Disclaimer · Privacy Statement

  • About UMHS
  • For Patients
  • For Health Professionals
  • For Researchers
  • Home
  • About
    ▼
    • What Is ALS?
    • Scott L. Pranger
    • National Advisory Board
    • Faculty & Staff
    • ALS Center of Excellence Brochure
  • Clinic
    ▼
    • Services
    • Your Visit to the ALS Clinic
    • Patient Portal
    • Durable Medical Equipment
    • Frequently Asked Questions
  • Research
    ▼
    • Clinical Trials
    • Observational Studies
    • Stem Cell Trial
    • Our Publications
    • Participate in Research at U-M
  • News
  • Patient Care Guide
    ▼
    • Nutrition
    • Living with ALS
    • Mobility & Independence
    • Patient & Family Support
  • Contact
  • NeuroNetwork
  • Make A Gift